Paramount BioSciences, LLC (“Paramount”) is a leading pharmaceutical development and investment company with its main focus on the biotechnology and life sciences sectors. With Paramount BioCapital, Inc., a FINRA registered broker-dealer in head of funding and raising capital for Portfolio companies, Paramount BioSciences heavily contributes to the emergence and development of innovative biotechnologies and life sciences.
Paramount BioScienses’ Model
Not only does Paramount BioSciences provide technical services and support, but is also engaged in new product development, biotech companies acquisition and development. It supports the newly created companies in several value-adding ways. They evaluate product candidates for the Portfolio companies, create development plans to facilitated the development process before, during, and after the formation of Portfolio Companies. Both, back-up and expertise is fully supported by BioSciences as it allows its Portfolio Companies to access to much more experienced infrastructure than they might have. This allows the company management to focus on the drug candidates’ development rather than building their own infrastructure. In many ways, this model developed by Paramount’s founder Lindsay Rosenwald provides both professional and “back office” support and limits delays in the development process, as well as maximized the returns for Portfolio companies and the patient community.
After approval and in-licensing, drug candidates are managed by a dedicated management team through the whole development cycle. Senior drug development staff at Paramount BioSciences, including Lindsay Rosenwald, supports Portfolio Companies in all aspects of pharmaceutical development. This includes formulation, clinical development, toxicology, manufacturing, quality assurance, and commercialization. With their extensive experience in developing leading pharmaceutical products, the Paramount’s team provides solutions for a variety therapeutical indications, starting from inflammation to cardiovascular to oncology to neurology and many other indications. Global network of consultants as well as industry leaders in the medical and scientific communities provide help during the candidates’ development and approval cycle.
With a proven track record, Paramount BioSciences helps Portfolio Companies recruit executives that will lead the new companies formed around the new compounds. Among the recent hires at Portfolio Companies, there are such executives as the former CEOs of Roche, Biogen, Sanofi-Aventis, Johnson&Johnson, Amgen and many others.
Over 20 years of financing and development of biomedical companies across a broad range of therapeutic indications, Lindsay Rosenwald in head of Paramount BioSciences nurtured more than 40 biotech companies. He builds companies from the ground up utilizing its own capital and then funds are raised from various private investors through Paramount Capital.
Paramount handles such important functions as accounting, legal, market analytical, financial functions. This helps its Portfolio companies focus on clinical studies and creating value for shareholders, licensors and patients.
With such a keen eye for finding and developing innovative drugs, Paramount BioSciences evaluates the quality and promises of drug candidates throughout the world, from small biotech firms and academic centers to large pharmaceutical corporations.
Paramount Process To Value Creation
What stands Paramount BioSciences out, is that their infrastructure and external network allows them to support Paramount Incubated Companies until they become self-sufficient. The development cycle has been developed by Lindsay Rosenwald in 1999 and can be described in a simple scheme similar to this one:
Product Assets à Paramount Initial Financing and Development àIncubation àPortfolio Company Formation à Value Inflection Point
Employees for each Portfolio Company are hired in accordance with developmental and financial circumstances. On average, most employees at Paramount have at least 15 years of experience in biotechnology or medical care sectors driving drug candidates through the regulatory and clinical value chain. Their expertize ranges from molecular biology to clinical medicine.
With such a deep experience across the drug development business, Lindsay Rosenwald has managed to build the team with leadership roles in the biotech market authorizations of numerous pharmaceutical products being sold worldwide, including Viracept, Neulasta, Rituxan, and Kepivance.
Paramount Business Units
Paramount Biosciences
With over 40 employees in 8 offices globally, Paramount BioSciences assess and negotiate for university and corporate biotechnology licenses. It develops and in-licenses compounds for various therapeutic indications – from inflammation and cardiology to neurology and cancer. Lindsay Rosenwald helps build standalone biotech companies that can attract capital and succeed as public companies
Paramount BioCapital, Inc.
Paramount BioCapital Inc. is a NASD-registered dealer that raises capital for the Portfolio Companies. It raised more than $1 billion and approximately $200 million in 2009. With their extensive expertise in securities transactions such as “PIPEs”, reverse mergers, self-registrations and private placements, Paramount BioCapital has become the leader in the biotechnology capital sector.
Paramount Corporate Development
Lindsay Rosenwald works closely with Paramount Corporate Development, which is involved in in-licensing and drug development activities. The Corporate Development group comprises of 20 industry veterans with a huge experience in all aspects of pharmaceutical development, including formulation, clinical operations, manufacturing and commercialization.
Paramount BioCapital Asset Management
Asset Management is responsible for purchasing and distributing equities of global healthcare companies. It has a proven hedge fund structure and assets under management in various private placement vehicles.
Paramount Acquisition Company
Paramount Acquisition Company creates unique private equity vehicles that match large capitals with late-stage private companies. It recently announced a $54 million transaction with Valeritas, which is a medical device company with its main FDA-approved insulin pump h-Patch.
Paramount BioSciences Executive Leadership Team
On average, Paramount BioSciences employees have 15 years of direct experience in the clinical and regulatory processes. Headed by Lindsay Rosenwald, the team members participated in dozens of pharmaceutical development and commercialization projects, including Rituxan, Viracept, Sutent, Kepivance, and Neulasta. More than 50 compounds currently undergo clinical development process and the products include drugs across a wide range of indications that include neurological disorders, metabolic conditions, infectious diseases and cancer.
Lindsay A. Rosenwald, M.D., is CEO and Chairman at Paramount BioSciences. His extensive experience in biotechnology, pharmacology and finance made him one of the leaders in the biotechnology and life sciences sectors. With more than 20 years of experience in developing and investing in biotechnology and life science companies, Dr. Lindsay Rosenwald founded and nurtured more than 40 biotech/pharma companies.
J. Jay Lobell, J.D., is President and Chief Operating Officer at Paramount BioSciences. His previous experience includes partnership at Covington & Burling, where he provided financial, regulatory, business, and litigation advice to financial institutions, corporations and individuals.
Russell Ellison, M.D., is Executive Vice President with over 30 years of senior management experience in pharmaceutical development and commercialization. He is a former Vice President Clinical Development at Fibrogen, Inc. and Chief Medical Officer of Sanofi-Synthelabo, USA. Dr. Ellison also served as the U.S. Vice President of Medical Affairs and is a former U.S. Vice President, Medical Affairs and Chief Medical Officer of Hoffman La Roche.
Advantages of Paramount BioSciences Model
What makes Paramount BioSciences a preferred acquirer of drugs and developer of biotechnologies is that Lindsay Rosenwald’s development team works with a global business development group that assesses and facilitates product and market opportunities. The offices of Paramount BioSciences are located worldwide, including New York City, London, Boston, Shanghai, San Diego, North Carolina, Orange County (California)). Promising drug candidates are moved forward quickly in the licensing process. Representatives of all areas in drug development cycle work together to ensure an agreement to move forward. The next step is the creation of product development plans for the compound and hiring management staff. At this stage, the compounds are transferred to Portfolio Companies with no transitional delay. The product candidates are supported through the clinical and regulatory process.
Paramount BioSciences has proved to rapidly execute deals and begin development work. Its access to the capital is an important part of any product development. It provides Portfolio companies with the structure that promotes drug candidate’s progression through to market, eliminating chances of program being shelved.
Clinical and commercial expertise at the company level helps Paramount Portfolio companies maximize value to in-licensed products.
History of Financial Wherewithal
Paramount BioSciences under the leadership of Lindsay Rosenwald has risen over $1 billion from outside investors in addition to their own investment in Paramount’s portfolio companies. All companies and clinical studies funded by the company receive substantial financing on all stages of the development cycle.
Lindsay Rosenwald has regular and close interaction with the leading US sell-side and buy-side institutions that include notable medical care investors, with whom Paramount’s hedge funds invest in the deals not directly involving the company itself. Paramount’s employees have real-time understanding of healthcare capital markets, which resulted in over $400 million funds for Portfolio Companies in 2009 year alone, including $200 million by Paramount. This includes $47 million for Cougar Biosciences in conjunction with SG Cowen, $37 million for Ziopharm Oncology, $22 MM for Chelsea Therapeutics and $16 million for Innovive Pharmaceuticals. Many of the premier healthcare funds financed in Paramount this year, which remains a good sign for the development of biotechnology and life sciences sectors.
